School of Infection & Immunity

Professor Irina Udalova

Title: Reprogramming neutrophil functional development

Synopsis:

During development neutrophils undergo extensive changes in nuclear morphology, gene expression programmes, and acquire specific effector functions. However, molecular mechanisms controlling neutrophil development remain largely unknown. Here we explore the role of key transcription factors in driving neutrophil maturation and acquisition of functions. 

Bio:

IU is Professor of Molecular Immunology, who is internationally recognised for pioneering new concepts in transcriptional regulation of the inflammatory response. She started her Genomics of Inflammation research group at the Kennedy Institute of Rheumatology, Imperial College London in 2005; and helped to shape the strategic directions of the Institute after its relocation to Oxford. She is now a Deputy Director of Research. Her research on macrophage and neutrophil genomics, supported by programmatic funding from the Wellcome Trust and MRC,  has revealed new insights into myeloid cell development and function including tissue maladaptation in disease.

First published: 19 May 2026

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